Tree like structure growing on human body due to Papilloma Virus




An Indonesian fisherman who feared that he would be killed by tree-like growths covering his body has been given hope of recovery by an American doctor - and Vitamin A.

Dede, now 35, baffled medical experts when warty "roots" began growing out of his arms and feet after he cut his knee in a teenage accident.
The welts spread across his body unchecked and soon he was left unable to carry out everyday household tasks.

Sacked from his job and deserted by his wife, Dede has been raising his two children - now in their late teens - in poverty, resigned to the fact that local doctors had no cure for his condition.

To make ends meet he even joined a local "freak show", parading in front of a paying audience alongside victims of other peculiar diseases.

Although supported by his extended family, he was often a target of abuse and ridicule in his rural fishing village.

But now an American dermatology expert who flew out to Dede's home village south of the capital Jakarta claims to have identified his condition, and proposed a treatment that could transform his life.
After testing samples of the lesions and Dede's blood, Dr Anthony Gaspari of the University of Maryland concluded that his affliction is caused by the Human Papilloma Virus (HPV), a fairly common infection that usually causes small warts to develop on sufferers.

Dede's problem is that he has a rare genetic fault that impedes his immune system, meaning his body is unable to contain the warts.

The virus was therefore able to "hijack the cellular machinery of his skin cells", ordering them to produce massive amounts of the substance that caused the tree-like growths known as "cutaneous horns" on his hands and feet.

Dede's counts of a key type of white blood cell are so low that Dr Gaspari initially suspected he may have the Aids virus.

But tests showed he did not, and it became clear that Dede's immune condition was something far rarer and more mysterious.

Warts aside, he had enjoyed remarkable good health throughout his life - which would not be expected of someone with a suppressed immune system - and neither his parents nor his siblings have shown signs of developing lesions.

"The likelihood of having his deficiency is less than one in a million," Dr Gaspari told the Telegraph.
Dr Gaspari, who became involved in the case through a Discovery Channel documentary, believes that Dede's condition can be largely cleared up by a daily doses of a synthetic form of Vitamin A, which has been shown to arrest the growth of warts in severe cases of HPV.

"He won't have a perfectly normal body but the warts should reduce in size to the point where he could use his hands," Dr Gaspari said.

"Over the course of three to six months the warts should be come smaller and fewer in number. He will be living a more normal life."

The most resilient warts could then be frozen off and the growths on his hands and feet surgically removed.

Dr Gaspari hopes to get the necessary drugs free of charge from pharmaceutical firms. They would then be administered by Indonesian doctors under his supervision.

Still intrigued by the origins of Dede's peculiar immune condition, the doctor would like to fly him to the United States for further examination, but fears the financial and bureaucratic barriers would prove too difficult to overcome.

"I would like to bring him to the US to run tests on where his immune condition has come from, but I would need funding and to get him a visa as well as someone to cover the costs of the tests," he said.

"I've never seen anything like this in my entire career."

Updates :
The “Tree Man”, Dede Koswara, appears more human after nine months of treatment. The treatment included removing the mass of warts, or “wood” from his body. 95% he recovered from warts.

4 comments:

Anonymous said...

I just see these photos at anonymous hpv dating site of pozgroup.com. Many members there say they never know there is such kind HPV.

bored.alaskan said...

It isn't the type of HPV. It's the man's immune system that is faulty. Apparently, per the above article, the man has an extremely rare faulty gene. THAT caused the 'hijacking' of the warts at the molecular level (I think I got that right! LOL). I certainly believe that this man is a modern one of a kind and that funding will NOT be a problem at all. The US and other countries, like Sweden, Germany, Holland, etc., also have fantastic research going on regarding our genetic makeup. Dede would be priceless to them - and likely, to the rest of humanity with the knowledge gained by his DNA. His children would receive far better educations in the western world, and Dede himself would get A+ medical care as long as he lived. I doubt that even after his death that his kids would be forgotten, as they, too, carry half their DNA from him. I wish him and his family the very best, and pray that Dr. Gaspari finds himself a great PR person to take things on!

Kingazerith2384 said...

Probably the worst part of Dede's dilemma was the fact that, instead of sticking with him, his wife just upped and left him....that's gotta hurt.

xPeeTx said...

imiquimod (Aldara) did wonders ... i had a mild outbreak of warts on my hands and couple on my feet about 10 years ago .... they would always come back after freezing them off, even cutting them out didn't work! then i scraped them and put aldara on them and covered tight with duct tape .... doctor recomended this .... and magically with in two weeks they all disappeared at once. strange treatment but true. i would take a bath in aldara if i was this guy .... eat it for breakfast even haha warts suck

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